Фото: Majid Asgaripour / WANA (West Asia News Agency) via Reuters
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In 2001, Hagan Bayley’s lab at Texas A&M demonstrated a limited sequencing method based on the observation that correctly and incorrectly paired DNA bases disrupted nanopore current to different extents. They tethered a short piece of DNA with a few unknown bases to the entrance of the nanopore, then added other short DNA strands with different bases at the position corresponding to the unknown base on the tethered strand. By looking at which base produced the disruption corresponding to a perfect match, they could guess the unknown nucleotide.
第十二条 自然保护区分为国家级自然保护区和省级自然保护区。
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